- What is the cause of OI?
- What is OI type 3 severe?
- What organs are affected by brittle bone disease?
- Can osteogenesis imperfecta be cured?
- Is Oi a disability?
- What is wrong with Byron the Baxter boy?
- How is OI diagnosed?
- What disease does Byron Baxter have?
- Is Osteogenesis Imperfecta painful?
- Can brittle bone disease be cured?
- How long can you live with osteogenesis imperfecta?
- What is OI in medical terms?
What is the cause of OI?
What causes osteogenesis imperfecta (OI).
OI is caused by defects in or related to a protein called type 1 collagen (pronounced KOL-uh-juhn).
Collagen is an essential building block of the body.
The body uses type 1 collagen to make bones strong and to build tendons, ligaments, teeth, and the whites of the eyes..
What is OI type 3 severe?
Osteogenesis imperfecta type III is a severe type of osteogenesis imperfecta (OI; see this term), a genetic disorder characterized by increased bone fragility, low bone mass and susceptibility to bone fractures.
What organs are affected by brittle bone disease?
Pulmonary: In people with severe forms of OI, respiratory complications are a leading cause of death. Although respiratory problems are usually more severe in those with severe OI, the primary collagen defect affects lung tissue in all people with OI, including those with a mild phenotype.
Can osteogenesis imperfecta be cured?
To date, there is no known treatment, medicine, or surgery that will cure osteogenesis imperfecta (OI). The goal of treatment is to prevent deformities and fractures and allow the child to function as independently as possible. Treatments for preventing or correcting symptoms may include: Care of fractures.
Is Oi a disability?
Most people with OI experience physical disability. OI also can cause weak muscles, brittle teeth, a curved spine, and hearing loss. Most forms of OI are caused by abnormal genes that are passed down from one or both parents to their children. There are currently 11 types of OI.
What is wrong with Byron the Baxter boy?
When you listen to 3-year-old Byron Baxter laugh and talk, you’d never know anything was wrong with him. But he was born with a rare condition called osteogenesis imperfecta, or brittle bone disease.
How is OI diagnosed?
The diagnosis of OI is made on the basis of family history and/or clinical presentation. Frequent fractures, short stature, a blue hue to the white part of the eye (blue sclera), teeth problems (dentinogenesis imperfecta) and hearing loss that progresses after puberty may be present.
What disease does Byron Baxter have?
That’s because Byron is living with a brittle bone disease, a rare genetic condition with no cure. Doctors call it osteogenesis imperfecta, which means “imperfectly formed bone.”
Is Osteogenesis Imperfecta painful?
Conclusions: Pain is a common occurrence for children with OI and is both acute and chronic in nature, interfering with children’s daily living activities. OI pain may not be optimally treated because many children experienced moderate to severe pain despite use of analgesics and/or coping strategies.
Can brittle bone disease be cured?
Brittle bone disease is a lifelong genetic disorder that causes your bones to break very easily, usually without any type of injury, as from a fall. Your doctor may also call it osteogenesis imperfecta. It affects both sexes and all races equally. There is no cure for brittle bone disease, but your doctor can treat it.
How long can you live with osteogenesis imperfecta?
Most children born with type I OI live normal, healthy lives into adulthood. Less severe symptoms do not affect life expectancy. Most OI-related deaths result from respiratory failure due to weak lungs. The most severe types will result in death at birth or soon after.
What is OI in medical terms?
Osteogenesis imperfecta (OI) is present at birth. It is often caused by a defect in the gene that produces type 1 collagen, an important building block of bone. There are many defects that can affect this gene.